study of d/g hemoglobin incidence in a sample population (single institution)

background:  the hemoglobin disorders constitute the most prevalent group of monogenic disease a findings consis tent with this is a hemoglobin/g variant indicating that the patient has hbd/g trait. hb d/g traits are clinically benign. in this study, the epidemiology of hbd/g was reviewed in a single institution in iran. methods and materials: we conducted the epidemiological study at aliasghar children's hospital and all patients with hbd/g were entered to this study. the hematological values, hemoglobin electrophoresis, peripheral blood smear and clinical findings were collected in the data special form. results:  among 11825 hemoglobin analysis performed, we detected 101 cases of hemoglobin d/g. there were 55.4% male and 44.6% female, median age 9±13.36 yrs. homozygous of d/g was found in seven pa tients with splenomegaly, jaundice, mild anemia and reticulocytosis. heterozygote patients were as ymptomatic. there wasn't any correlation between hbd/g with serum ferritin, mcv, hb and sex. conclusion: in iran hbd/g is relatively benign condition with mild anemia, poikylocytosis and minimal hemolysis.